NusA Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis on E.coli cell lysates using anti- NusA Mouse mAb (Cat. # M1307-1).
Host Species; Species ReactivityMouse; E.coli
Application SummaryWB, ELISA
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesTranscription termination/antitermination protein NusA,N utilization substance protein A,Transcription termination/antitermination L factor
BackgroundNusA is a key component in both prevention and enhancement of transcriptional termination. It is important in both Rho-dependent and intrinsic termination, as well as in lambda and other phage antitermination systems. The gene was first identified by isolation of the nusAl mutation, which restricts bacteriophage l growth by preventing the antitermination activity of the l N protein. NusA is involved in transcriptional antitermination in the cell. It has been shown to specifically aid in read-through of the RNA polymerase genes rpoB and rpoC, as well as in successful synthesis of the ribosomal RNA genes.(M1307-1)