Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)

Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)

SKU: CA51-10ug
$105.00Price
Recombinant Human Prostaglandin-D2 Synthase is produced by our Mammalian expression system and the target gene encoding Ala23-Gln190 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CA51
Size
  • Accession Number

    P41222
  • Background

    Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system.
  • Expression

    Human Cells
  • Packaging

    Dry ice/ice packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5.
  • ALTnames

    Prostaglandin-H2 D-Isomerase, Beta-Trace Protein, Cerebrin-28, Glutathione-Independent PGD Synthase, Lipocalin-Type Prostaglandin-D Synthase, Prostaglandin-D2 Synthase, PGD2 Synthase,PGDS, PGDS2, PTGDS, PDS

(800) 943-6396

150 Essex St, Millburn, NJ 07041, USA

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