Recombinant Human Karyopherin Subunit α-2 /KPNA2/IPOA1 (N-6His)
Recombinant Human Importin alpha 2 is produced by our E.coli expression system and the target gene encoding Met1-Phe529 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CE62
BackgroundKaryopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.
PackagingDry ice/ice packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM TrisHCl,1mM DTT,20% Glycerol, pH 8.0 .
ALTnamesImportin Subunit Alpha-2, Karyopherin Subunit Alpha-2, RAG Cohort Protein 1, SRP1-Alpha, KPNA2, RCH1, SRP1