Recombinant Human Interleukin-37 is produced by our E.coli expression system and the target gene encoding Lys53-Asp218 is expressed. Bon Opus Cat. #C073
Recombinant Human Interleukin-37/IL-37
SKU: C073-10ug
$158.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
Q9NZH6
Species
Human
Expression System
E.coli
Target Sequence
Lys53-Asp218
Tag
tag free
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 2mM DTT, pH 7.4.
Packaging
Ambient
Background
Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues proprotein containing a 45 amino acid propeptide, which is cleaved to generate mature protein. IL1F7b binds to IL18 Rα with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Interleukin-37; FIL1 Zeta; IL-1X; Interleukin-1 Family Member 7; IL-1F7; Interleukin-1 Homolog 4; IL-1H; IL-1H4; Interleukin-1 Zeta; IL-1 Zeta; Interleukin-1-Related Protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1
Alternative Names
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Citation
Immobilized Human IL-37 (Cat#C073) at 2ug/ml (100 μl/well) can bind Human IL-18RAP-Fc . The ED50 of Human IL-37 (Cat#C073) is 0.5-2.5μg/ml .
Activity
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