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Recombinant Human Interleukin-33/IL-33 (N-6His)
Recombinant Human Interleukin-33 is produced by our E.coli expression system and the target gene encoding Ser112-Thr270 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #C233

Recombinant Human Interleukin-33/IL-33 (N-6His)

SKU: C233-10ug
$158.00Price
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
O95760
Species
Human
Expression System
E.coli
Target Sequence
Ser112-Thr270
Tag
N-His
Formulation
Lyophilized from a 0.2 um filtered solution of PBS,1mM DTT, PH7.4.
Packaging
Ambient
Background
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Alternative Names
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Citation
NA
Activity
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