Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

SKU: CF53-10ug
Recombinant Human Estrogen Receptor Beta is produced by our E.coli expression system and the target gene encoding Met1-Ala323 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CF53
  • Accession Number

  • Background

    Estrogen Receptor Beta (ESR2) is a nuclear protein that belongs to the nuclear hormone receptor family of NR3 subfamily. It contains one nuclear receptor DNA-binding domain and is expressed in many tissues at a lower level. ESR2 is a nuclear hormone receptor. It binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
  • Expression

  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl,pH8.0.
  • ALTnames

    Estrogen Receptor Beta, ER-Beta, Nuclear Receptor Subfamily 3 Group A Member 2, ESR2, ESTRB, NR3A2

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