top of page

Contact us to order

Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

Distributors

Shipping Info

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

Please contact us to order for  international shipment.

[{"key":"C688-500ug","value":"Backorder"},{"key":"C688-1mg","value":"Backorder"},{"key":"C688-50ug","value":"Backorder"},{"key":"C688-10ug","value":"In Stock"}]
Recombinant Human Dickkopf-Related Protein 1/DKK1 (N-8His)

Recombinant Human Dickkopf-Related Protein 1/DKK1 (N-8His)

SKU: C688-10ug
$158.00Price
Recombinant Human Dickkopf-related protein 1 is produced by our Mammalian expression system and the target gene encoding Thr32-His266 is expressed with a 8His tag at the N-terminus. Bon Opus Cat. #C688
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
O94907
Species
Human
Expression System
Human Cells
Target Sequence
Thr32-His266
Tag
N-His
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Dickkopf-related protein 1;Dickkopf-1;Dkk-1
Alternative Names
Be the first to submit a citation to get publication rewards
Citation
NA
Activity
  • twitter
  • linkedin
bottom of page