Accession Number
P10599
Endotoxin
Species
Expression System
Less than 0.1 ng/ug (1 EU/ug)
Human
E. coli
Target Sequence
Tag
M1-V105
C-Avi&6His
Formulation
Packaging
Lyophilized frum a 0.2 um filtered solution of 2umM Na2HPO4, 2umM NaH2PO4, pH7.4.
Ambient
Thioredoxin1; Thioredoxin-1; Trx1; TXN; TXN1
Background
Alternative Names
Thioredoxin (TXN) is a small ubiquitous protein in all cells that plays an important role in cellular redox reactions. It is secreted by lymphocytes, hepatocytes, fibroblasts, and several tumor cells. TXN is up-regulated under stress conditions such as hypoxia, elevated hydrogen peroxide concentrations, photochemical oxidative stress, and viral and bacterial infections. TXN modulates the growth factor activities, and the antioxidant properties, as well as act as a cofactor that provides reducing equivalents, and transcriptional regulation.