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Noggin Rabbit polyclonal Antibody IgG

SKU: BA110511-100µl
$279.00Price

Fig1: Western blot analysis of Noggin on MG-63 cell lysate using anti-Noggin antibody at 1/1,000 dilution.

Fig2: ICC staining Noggin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: ICC staining Noggin in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bon Opus Cat. #BA110511
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    This antibody is produced by immunizing rabbits with a synthetic Peptide (KLH-coupled) corresponding to a region of Noggin.
  • Application Summary

    WB, ICC, IHC
  • Purification; Formulation

    Immunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Noggin
  • Background

    Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. Murine Noggin is expressed in condensing cartilage and immature chondrocytes, as are many BMPs. It is essential for cartilage morphogenesis and joint formation. Defects in NOG are the cause of multiple synostoses syndrome 1 (SYNS1), symphalangism proximal syndrome (SYM1) and tarsal-carpal coalition syndrome (TCC).(0805-2)