Neuropilin 1 Mouse monoclonal Antibody IgM
Fig1: Western blot analysis on recombinant protein using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
Fig2: Immunofluorescent staining of Hela cells using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
Fig3: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
Host Species; Species ReactivityMouse; Human, Mouse
Application SummaryWB, ICC, IHC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesNeuropilin-1,Vascular endothelial cell growth factor 165 receptor,CD_antigen: CD304
BackgroundThe membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.(M0910-5)