N-Cadherin Mouse monoclonal Antibody IgM

SKU: BA110492-100µl

Fig1: Western blot analysis on mouse heart (1) and human heart (2) lysates using anti-N-Cadherin mouse mAb.

Fig2: Immunofluorescent staining of A549 cells using anti-N-Cadherin mouse mAb.

Fig3: Immunohistochemical analysis of paraffin- embedded human lung cancer tissue using anti-N-Cadherin mouse mAb.

Bon Opus Cat. #BA110492
  • Host Species; Species Reactivity

    Mouse; Human, Mouse
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, ICC, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Cadherin-2,CDw325,Neural cadherin,CD_antigen: CD325
  • Background

    The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events. The cadherin subfamily includes N-, P-, B-, and E- cadherins, and other members. Recent studies indicate that cancer cells have up-regulated N-cadherin in addition to loss of E-cadherin. This change in cadherin expression is called the "cadherin switch". N-cadherin cooperates with the FGF receptor, leading to overexpression of MMP-9 and cellular invasion.(M1304-1)

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