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MTERFD1 Mouse monoclonal Antibody IgG1

SKU: BA110885-100µl
$279.00Price

Fig1: Western blot analysis of MTERFD1 on different lysates using anti-MTERFD1 antibody at 1/1,000 dilution.

Positive control:

Lane 1: Hela

Lane 2: Mouse kidney tissue

Lane 3: K562

Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MTERFD1 antibody. Counter stained with hematoxylin.

 

Bon Opus Cat. #BA110885
Size
  • Host Species; Species Reactivity

    Mouse; Human, Mouse
  • Immunogen

    Recombinant protein
  • Application Summary

    WB,IHC,ICC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Transcription termination factor 3, mitochondrial, Mitochondrial transcription termination factor 3, mTERF domain-containing protein 1, mitochondrial
  • Background

    MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.(EM1701-29)