MSY2 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of MYS2 on MCF-7 cell (1) and mouse testis tissue lysate using anti-MSY2 antibody at 1/1,000 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-MSY2 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityMouse; Human, Mouse, Rat
Purification; FormulationProG affinity purified; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesY-box-binding protein 2, Contrin, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2 homolog
BackgroundMajor constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.(EM1701-40)