MRKN2 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on cell lysates using anti-MARKN2 rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded human colorectal carcinomas tissue using anti- MRKN2 rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse
Application SummaryWB, ICC, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesProbable E3 ubiquitin-protein ligase makorin-2,RING finger protein 62
BackgroundMKRN2 gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) gene in an antisense orientation and may have a co-regulatory function with RAF1. Alternative splicing results in multiple transcript variants. E3 ubiquitin ligase catalyze the covalent attachment of ubiquitin moieties onto substrate proteins.(R1312-14)