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MLKL (phospho S345) Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112331-100µl
$279.00Price

Fig1: Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin.  

 

Fig2: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112331
Size
  • Host Species; Species Reactivity

    Rabbit; Mouse
  • Immunogen

    Synthetic phospho-Peptide corresponding to residues surrounding Ser345 of human MLKL.
  • Application Summary

    IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Mixed lineage kinase domain-like protein
  • Background

    Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.(ET1705-51)