Matrin 3 Recombinant Rabbit monoclonal Antibody IgG

Matrin 3 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112470-100µl
$279.00Price

Fig1: Western blot analysis of Matrin 3 on different lysates using anti-Matrin 3 antibody at 1/1,000 dilution.

 Positive control:

 Lane 1: Daudi

    Lane 2: Mouse brain tissue

 

Fig2: ICC staining Matrin 3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: ICC staining Matrin 3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bon Opus Cat. #BA112470
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB,ICC,IF,IHC,FC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Matrin-3
  • Background

    Matrin-3 is a nuclear matrix protein containing one matrin-type zinc finger and two RRM (RNA recognition motif) domains. Matrin-3 plays a role in transcription and may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the PSF-p54/NRB heteromer, Matrin-3 may play a role in the nuclear retention of defective RNAs. As the main substrate for PKA-mediated phosphorylation, Matrin-3 may serve as a rapid way of transferring information from synapses containing NMDA receptors to neuronal nuclei under physiological conditions. Also, the phosphorylation of Matrin-3 may contribute to neuronal death under pathological conditions. It is likely that Matrin-3 activity is regulated by calcium dependent interaction with CaM I and also by caspase induced cleavage.(ET7106-95)

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