MATER Rabbit polyclonal Antibody IgG

SKU: BA110457-100µl

Fig1: ICC staining MATER in mouse blastocyst and 2-cell stage embryo (red). Cells were incubated overnight at 4



Bon Opus Cat. #BA110457
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse
  • Immunogen

  • Application Summary

  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    NACHT, LRR and PYD domains-containing protein 5,Mater protein homolog
  • Background

    NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function.(ER50101)

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