LRG1 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of LRG1 on human serum using anti-LRG1 antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LRG1 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
BackgroundLRG1 (leucine-rich alpha-2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains eight LRR (leucine-rich repeats) and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).(ET7107-11)