LDHA Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of LDHA on different cell lysates using anti-LDHA antibody at 1/500 dilution.
Lane 1: A549
Lane 2: Hela
Lane 3: A431
Lane 4: 293
Lane 5: Jurkat
Lane 6: MCF-7
Lane 7: Human liver
Lane 8: Human kidney
Lane 9: Human brain
Lane 10: Human thymus
Fig2: Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, IHC, FC
Purification; FormulationPeptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesL-lactate dehydrogenase A chain,Cell prolifeRation-inducing gene 19 protein,LDH muscle subunit,Renal carcinoma antigen NY-REN-59
BackgroundLactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.(ER00702)