LDH-A Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis on A549 cell lysates using anti-LDH-A Mouse mAb (Cat. #M1007-7).
Fig2: Immunohistochemical analysis of paraffinembedded mouse testis tissue using anti-LDH-A Mouse mAb (Cat. # M1007-7).
Host Species; Species ReactivityMouse; Human, Mouse
Application SummaryWB, IHC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesL-lactate dehydrogenase A chain,Cell prolifeRation-inducing gene 19 protein,LDH muscle subunit,Renal carcinoma antigen NY-REN-59
BackgroundLactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.(M1007-7)