LASS2 Mouse monoclonal Antibody IgG2b
Fig1: Western blot analysis on K562-AO2 cell lysates using anti-lass2 monoclonal antibody.
Fig2: Western blot analysis of LASS2 in on hybrid fish (crucian-carp) brain tissue lysate using anti-LASS2 antibody at 1/500 dilution.
Fig3: ICC staining LASS2 (red) in K562 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Host Species; Species ReactivityMouse; Human, Zebrafish
Application SummaryWB, ICC, IHC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesCeramide synthase 2,LAG1 longevity assurance homolog 2,SP260,Tumor metastasis-suppressor gene 1 protein
BackgroundThe LAG1 gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.(M1006-6)