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LAMP2a Rabbit polyclonal Antibody IgG

SKU: BA111139-100µl
$279.00Price

Fig1: Western blot analysis of LAMP2a on mouse placenta tissue lysates using anti-LAMP2a antibody at 1/1,000 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111139
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse
  • Immunogen

    Synthetic Peptide within C-terminal human LAMP2a.
  • Application Summary

    WB,IHC
  • Purification; Formulation

    Peptide affinity purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Lysosome-associated membrane glycoprotein 2, CD107 antigen-like family member B, LGP-96, CD_antigen: CD107b
  • Background

    Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.(ER1802-99)