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LAMP1 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111998-100µl
$279.00Price

Fig1: Western blot analysis of LAMP1 on different lysates using anti-LAMP1 antibody at 1/1,000 dilution.

Positive control:   

Lane 1: Hela           

Lane 2: Jurkat

Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP1 antibody. Counter stained with hematoxylin.

 

Bon Opus Cat. #BA111998
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Lysosome-associated membrane glycoprotein 1, CD107 antigen-like family member A, CD_antigen: CD107a
  • Background

    Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107a) and LAMP-2 (also designated CD107b) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans-Golgi network and are transported intracellularly via a pathway that is distinct from the Clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of Thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.(ET1701-94)