KLF4 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on 293 (1) and F9 (2) cell lysates using anti-KLF4 rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-KLF4 rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, IHC, FC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesKrueppel-like factor 4,Epithelial zinc finger protein EZF,Gut-enriched krueppel-like factor
BackgroundKLF4 is a member of the erythroid Kruppel-like factor (EKLF) multigene family that is highly expressed in the differentiating layers of the epidermis. KLF4 plays a critical role in the differentiation of epithelial cells and is essential for normal gastric homeostasis. It regulates the expression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.(R1308-1)