Kir3.4 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of Kir3.4 on different lysates using anti-Kir3.4 antibody at 1/500 dilution.
Lane 1: Mouse heart
Lane 2: Rat heart
Fig2: ICC staining Kir3.4 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining Kir3.4 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
ImmunogenSynthetic Peptide within N-terminal human Kir3.4.
Purification; FormulationPeptide affinity purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesG protein-activated inward rectifier potassium channel 4, Cardiac inward rectifier, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, KATP-1, Potassium channel, inwardly rectifying subfamily J member 5
BackgroundThis potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.(ER1803-03)