kinase D-interacting substrate 220 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis on recombinant protein using anti-Kidins220 Mouse mAb (Cat. # M0910-4).
Fig2: Immunofluorescent staining of F9 cells using anti-Kidins220 Mouse mAb (Cat. # M0910-4).
Fig3: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-Kidins220 Mouse mAb (Cat. # M0910-4).
Host Species; Species ReactivityMouse; Mouse
Application SummaryWB, ICC, IHC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
BackgroundKinase D-interacting substrate 220 (Kidins220), also known as ARMS (ankyrin-rich membrane spanning) is an integral plasma membrane protein predominantly expressed in brain and neurons that presents a polarized location in neural cells, concentrating at the tip of extending neurites and in plasma membrane micro-domains corresponding to lipid rafts. The primary amino acid sequence of Kidins220 reveals 11 ankyrin repeats, 4 trans-membrane domains, a proline-rich region, a sterile-α motif (or SAM) domain, and a type I postsynaptic density-95/discs large/zonula occludens-1 (PDZ)-binding motif at the very C-terminus.(M0910-4)