KHSRP Mouse monoclonal Antibody IgG
Fig1: Western blot analysis of KHSRP on Jurkat cell lysate using anti-KHSRP antibody at 1/500 dilution.
Fig2: Flow cytometric analysis of HT-29 cells with KHSRP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.
Host Species; Species ReactivityMouse; Human, Mouse, Rat
ImmunogenSynthetic Peptide within human KHSRP aa 600-700.
Purification; FormulationProG purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesFar upstream element-binding protein 2, KH type-splicing regulatory protein, p75
BackgroundBinds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.(EM1701-97)