K2P4.1 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of K2P4.1 on different lysates using anti-K2P4.1 antibody at 1/500 dilution.
Lane 1: Mouse colon
Lane 2: Rat kidney
Fig2: Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse
ImmunogenSynthetic Peptide within human K2P4.1 aa 320-380.
Purification; FormulationPeptide affinity purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesPotassium channel subfamily K member 4, TWIK-related arachidonic acid-stimulated potassium channel protein, Two pore potassium channel KT4.1
BackgroundK2P4.1 (also named TWIK-related arachidonic acid stimulated K+ channel, TRAAK or KCNK4) is a member of the 2-pore (2P) domain K+ channels family that at the moment includes 15 members. These channels show little time or voltage dependence and are considered to be “leaky” or “background” K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation. The K2P channels have a signature topology that includes four transmembrane domains and two pore domains with intracellular N- and C- termini.(ER1803-07)