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IL13 Receptor alpha 1 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112438-100µl
$279.00Price

Fig1: Western blot analysis of IL13 Receptor alpha 1 on A549 cell lysates using anti-IL13 Receptor alpha 1 antibody at 1/500 dilution.

Fig2: ICC staining IL13 Receptor alpha 1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-IL13 Receptor alpha 1 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112438
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB,ICC,IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Interleukin-13 receptor subunit alpha-1, Cancer/testis antigen 19, CD_antigen: CD213a1
  • Background

    Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.(ET7106-61)