IgG4 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111582-100µl
$279.00Price

Fig1: Western blot analysis of IgG4 on human plasma lysates using anti-IgG4 antibody at 1/1,000 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IgG4 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IgG4 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111582
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Ig gamma-4 chain C region
  • Background

    The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.(ET1609-56)

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