IDH2 Recombinant Rabbit monoclonal Antibody IgG

IDH2 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112287-100µl
$279.00Price

Fig1: Western blot analysis of IDH2 on different cell lysate using anti-IDH2 antibody at 1/1,000 dilution.

  Positive control:

  Line 1: Mouse heart   

     Line 2: Rat heart

  Line 3: 293T

 

Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-IDH2 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IDH2 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112287
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC, FC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    IsocitRate dehydrogenase [NADP], mitochondrial, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase
  • Background

    IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.(ET1704-93)

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