Hsp60 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111571-100µl
$279.00Price

Fig1: Western blot analysis of Hsp60 on different lysates using anti-Hsp60 antibody at 1/1,000 dilution.

Positive control:   

Lane 1: Hela          

Lane 2: MCF-7 

Lane 3: PANC-1        

Lane 4: SW480

Fig2: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Hsp60 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Hsp60 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111571
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, Chaperonin 60, Heat shock protein 60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein
  • Background

    The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent poly-peptide chains across cellular membranes, and the regulation of protein folding. HSPs (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins, and the HSP 110 family. The constitutively expressed mitochondrial protein HSP 60 shares the ability to recognize and stabilize proteins during folding, assembly and disassembly with other HSP family members. The mitochondrial and cytosolic localization of HSP 60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition.(ET1609-45)

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