HP1 alpha Mouse monoclonal Antibody IgG1

SKU: BA110355-100µl

Fig1: Western blot analysis on MCF-7 cell lysates using anti-HP-1αMouse mAb (Cat. # M1211-2).

Fig2: Immunofluorescent staining of MCF-7 cells using anti-HP-1α Mouse mAb (Cat. # M1211-2).


Bon Opus Cat. #BA110355
  • Host Species; Species Reactivity

    Mouse; Human, Mouse
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, ICC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Chromobox protein homolog 5,Antigen p25,Heterochromatin protein 1 homolog alpha
  • Background

    The family of Heterochromatin Protein 1 (HP1) ("Chromobox Homolog", CBX) are highly conserved adapter proteins, which have important functions in the cell nucleus. These functions include gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin.Three different paralogs of HP1 are found in mammals, HP1α, HP1βand HP1γ.(M1211-2)

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