HLA-DQA1 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of HLA-DQA1 on different lysates using anti-HLA-DQA1 antibody at 1/1,000 dilution.
Lane 1: Rat lung
Lane 2: Rat skin
Lane 3: Mouse thymus
Lane 4: Mouse spleen
Lane 5: Raji
Fig2: Immunohistochemical analysis of paraffin-embedded rat lung tissue using anti-HLA-DQA1 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-HLA-DQA1 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesHLA class II histocompatibility antigen, DQ alpha 1 chain, DC-1 alpha chain, DC-alpha, HLA-DCA, MHC class II DQA1
BackgroundMajor histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also denotes the genetic locus which contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.HLA-DQA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen-presenting cells.(ET1706-51)