Histone H4 (tri methyl K20) Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111545-100µl
$279.00Price

Fig1: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Histone H4 (tri methyl K20) antibody. Counter stained with hematoxylin.

Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Histone H4 (tri methyl K20) antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Histone H4 (tri methyl K20) antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111545
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Histone H4
  • Background

    Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fibers. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which is comprised of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Human and mouse Histone H4 are subject to trimethylation at Lys 20, a modification that may be necessary for select DNA transactions or chromatin state transitions.(ET1609-16)

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