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GPX4 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112422-100µl

Fig1: Western blot analysis of GPX4 on different lysates using anti-GPX4 antibody at 1/500 dilution.

 Positive control:

 Lane 1: Rat liver  

   Lane 2: Mouse kidney  

 Lane 3: Human liver 

      Lane 4: Jurkat


Fig2: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GPX4 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112422
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat, Zebrafish
  • Immunogen

    Recombinant protein
  • Application Summary

  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, Glutathione peroxidase 4
  • Background

    Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.(ET1706-45)