GPX1 Mouse monoclonal Antibody IgG
Fig1: Western blot analysis of Glutathione Peroxidase 1 on THP-1 cell lysate using anti- Glutathione Peroxidase 1 antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti- Glutathione Peroxidase 1 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- Glutathione Peroxidase 1 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityMouse; Human
ImmunogenRecombinant protein within human Glutathione Peroxidase 1 aa 20-250.
Purification; FormulationProG purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesGlutathione peroxidase 1, Cellular glutathione peroxidase
BackgroundThe protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide.(EM1701-96)