Gp83 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of Gp83 on SH-SY-5Y cells lysates using anti-Gp83 antibody at 1/1,000 dilution.
Fig2: ICC staining Gp83 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-Gp83 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityMouse; Human, Mouse, Rat
Purification; FormulationProG affinity purified; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesDisintegrin and metalloproteinase domain-containing protein 7, Sperm maturation-related glycoprotein GP-83
BackgroundThis gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein.(EM1701-53)