GM-CSF-R-alpha (CD116) Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on F9 cell lysates using anti- GM-CSF-R-alpha polyclonal antibody.
Host Species; Species ReactivityRabbit; Mouse
Application SummaryWB, ICC, IHC, FC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesGranulocyte-macrophage colony-stimulating factor receptor subunit alpha,CD_antigen: CD116
BackgroundThe granulocyte macrophage–colony-stimulating factor receptor (GM-CSF-R) is a heterodimer composed of 2 subunits,αand b, and ligand binding to the high-affinity receptor leads to signalling for the multiple actions of GM-CSF on target cells. The GM-CSF receptors are found on the surface of myeloid precursors, granulocytes, mononuclear phagocyte, and also frequently present on the myeloid malignancies. The GM-CSF-R-alpha transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.(0804-8)