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GLUT2 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111932-100µl
$279.00Price

Fig1: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.

Fig2: Immunohistochemical analysis of paraffin-embedded human kideny tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111932
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC, FC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver
  • Background

    Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut2 expression is seen in pancreatic beta cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.(ET1701-34)