GLUR Rabbit polyclonal Antibody IgG

SKU: BA111136-100µl

Fig1: Western blot analysis of GLUR on different lysates using anti-GLUR antibody at 1/2,000 dilution.

 Positive control:

 Lane 1: A549 

    Lane 2: Rat liver tissue


Fig2: ICC staining GLUR in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GLUR antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111136
  • Host Species; Species Reactivity

    Rabbit; Human, Rat
  • Immunogen

    Recombinant protein within human GLUR 260-450 aa.
  • Application Summary

  • Purification; Formulation

    Protein affinity purified. ; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Glutathione reductase, mitochondrial
  • Background

    Glutathione plays a key role in maintaining proper function and preventing oxidative stress in human cells. It can act as a scavenger for hydroxyl radicals, singlet oxygen, and various electrophiles. Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn reduces hydrogen peroxide (H2O2), a dangerously reactive species within the cell. In addition, it plays a key role in the metabolism and clearance of xenobiotics, acts as a cofactor in certain detoxifying enzymes, participates in transport, and regenerates antioxidants such and Vitamins E and C to their reactive forms. The ratio of GSSG/GSH present in the cell is a key factor in properly maintaining the oxidative balance of the cell, that is, it is critical that the cell maintains high levels of the reduced glutathione and a low level of the oxidized Glutathione disulfide. This narrow balance is maintained by glutathione reductase, which catalyzes the reduction of GSSG to GSH.(ER1802-96)

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