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Glucose Transporter GLUT4 Rabbit polyclonal Antibody IgG

SKU: BA110306-100µl

Fig1: Western blot analysis on cell lysates using anti-GLUT4 rabbit polyclonal antibodies.

Fig2: ICC staining GLUT4 in MCF-7 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GLUT4 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA110306
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse
  • Immunogen

  • Application Summary

  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Solute carrier family 2, facilitated glucose transporter member 4,Glucose transporter type 4, insulin-responsive
  • Background

    GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac) that is responsible for insulin-regulated glucose transport into the cell. Under conditions of low insulin, GLUT4 is sequestered in intracellular vesicles in muscle and fat cells. Insulin induces a rapid increase in the uptake of glucose by inducing the translocation of GLUT4 from these vesicles to the plasma membrane. Muscle contraction stimulates muscle cells to translocate GLUT4 receptors to their surfaces. This is especially true in cardiac muscle, where continuous contraction can be relied upon; but is observed to a lesser extent in skeletal muscle.(R1402-3)