Gemin 1 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112622-100µl
$279.00Price

Fig1: Western blot analysis of Gemin 1 on SiHa cell lysates using anti-Gemin 1 at 1/500 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-Gemin 1 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Gemin 1 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA112622
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein within human Gemin 1 aa 1-200.
  • Application Summary

    WB,IHC,IP
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Survival motor neuron protein, Component of gems 1, Gemin-1
  • Background

    The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development. Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).(ET7108-63)

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