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GAPDH (HRP conjugated) Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112069-100µl
$279.00Price
 
  
  
 
    
Fig1: Western blot analysis of GAPDH on different lysates using anti-GAPDH antibody at 1/1,000 dilution.
 
Positive control: 
 
  Lane 1: Hela 
 
  Lane 2: PC-12 
 
  Lane 3: NIH/3T3
 
 
 
 
 		 
  
 
 

 Bon Opus Cat. #BA112069
Size
100 µl

  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat, Monkey, Chicken, Fish

  • Immunogen

    Recombinant protein

  • Application Summary

    WB

  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.

  • ALTnames

    Glyceraldehyde-3-phosphate dehydrogenase, Peptidyl-cysteine S-nitrosylase GAPDH

  • Background

    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. While GAPDH has long been recognized as playing an integral role in glycolysis, additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the β-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.(ET1702-66)