gamma Sarcoglycan Recombinant Rabbit monoclonal Antibody IgG

gamma Sarcoglycan Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112225-100µl
$279.00Price

Fig1: Western blot analysis of gamma Sarcoglycan on human skeletal muscle cells lysates using anti- gamma Sarcoglycan antibody at 1/500 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-gamma Sarcoglycan antibody. Counter stained with hematoxylin.

 

Bon Opus Cat. #BA112225
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IP, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Gamma-sarcoglycan, 35 kDa dystrophin-associated glycoprotein
  • Background

    The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.(ET1704-24)

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