ESRRB Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on A549 (1) and F9 (2) cell lysates using anti-ESRRB rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti- ESRRB rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-ESRRB rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, ICC, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesSteroid hormone receptor ERR2,ERR beta-2,Estrogen receptor-like 2,Estrogen-related receptor beta,Nuclear receptor subfamily 3 group B member 2
BackgroundSteroid hormone receptors are found on the plasma membrane, in the cytosol and also in the nucleus of target cells. They are generally intracellular receptors and initiate signal transduction for steroid hormones which lead to changes in gene expression over a time period of hours to days. Defects in ESRRB are the cause of deafness autosomal recessive type 35 (DFNB35). DFNB35 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.(R1308-2)