EpCAM Recombinant Rabbit monoclonal Antibody IgG

EpCAM Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111506-100µl
$279.00Price

Fig1: Western blot analysis of EpCAM on different lysates using anti-EpCAM antibody at 1/1,000 dilution.

Positive control: 

  Lane 1: HCT116 

  Lane 2: SW480

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111506
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Epithelial cell adhesion molecule, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, CD_antigen: CD326
  • Background

    EPCAM is a carcinoma-associated antigen and belongs to a family which includes at least 2 type I membrane proteins. The EPCAM protein has a role in embryonic stem cells proliferation and differentiation. EPCAM is used as a target for immunotherapy treatment of human carcinomas. EPCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and acts as a homotypic calcium-independent cell adhesion molecule. Epithelial cell adhesion molecules (EPCAM) can act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for supplying immunological barrier as a first line of defense against mucosal infection. EPCAM gene mutations result in congenital tufting enteropathy.(ET1608-26)

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