eNOS Rabbit polyclonal Antibody IgG
Fig1: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti- eNOS rabbit polyclonal antibody.
Fig2: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti- eNOS rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human mammary gland tissue using anti-eNOS rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesNitric oxide synthase, endothelial,Constitutive NOS,EC-NOS,Endothelial NOS,NOS type III
BackgroundEndothelial NOS (eNOS), also known as nitric oxide synthase 3 (NOS3), generates NO in blood vessels and is involved with regulating vascular function. The gene coding for eNOS is located on Chromosome 7. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. A constitutive Ca2+ dependent NOS provides a basal release of NO. eNOS is associated with "caveolae" a component of plasma membranes surrounding cells, and the membranes of Golgi bodies within cells. eNOS localisation to endothelial membranes is mediated by cotranslational N-terminal myristoylation and post-translational palmitoylation.(R1412-3)