Dystrophin Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112101-100µl
$279.00Price

Fig1: Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Dystrophin antibody. Counter stained with hematoxylin.

Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Dystrophin antibody. Counter stained with hematoxylin.

 

Bon Opus Cat. #BA112101
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Dystrophin
  • Background

    Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least eight independent tissue-specific promoters and two poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002% of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.(ET1702-98)

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