DDAH2 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA112514-100µl

Fig1: Western blot analysis of DDAH2 on different tissue lysates using anti-DDAH2 antibody at 1/2,000 dilution.

 Positive control:

 Lane 1: Rat heart

     Lane 2: Mouse heart

 Lane 3: Mouse lung

    Lane 4: Human lung




Bon Opus Cat. #BA112514
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Synthetic Peptide within Human DDAH2 aa 1-100
  • Application Summary

  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    N(G),N(G)-dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase protein
  • Background

    DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.(ET7107-41)

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